Depression and Depression Relating Variables in Hemopoietic Stem Cell Transplantation Recipients with Leukemia

Lee, So-Young; Park, Ho Ran

doi:2006.15.1.89

J Korean Acad Psychiatr Ment Health Nurs > Volume 15(1); 2006 > Article

Original Article

Journal of Korean Academy of psychiatric and Mental Health Nursing 2006;15(1):89-98.
DOI: https://doi.org/10.12934/jkpmhn.2006.15.1.89 Published online March 31, 2006.

Depression and Depression Relating Variables in Hemopoietic Stem Cell Transplantation Recipients with Leukemia

So-Young Lee¹, Ho Ran Park²

¹Department of Nursing. College of Catholic Sangji, Korea
²College of Nursing. The Catholic University of Korea

조열모세포이식을 받은 백혈병 환자의 우울과 우울영향요인

이소영¹, 박호란²

¹가톨릭상지대학 간호과
²가톨릭대학교 간호대학

Correspondence: Ho Ran Park, Tel: +82-2-590-1291, Fax: +82-2-590-1297,
Email: hrpark@catholic.ac.kr

Received: 9 January 2006 • Accepted: 8 March 2006

Abstract

Purpose
This study aimed to understand the depression in hemopoietic stem cell transplantation(HSCT) with leukemia and to analyze the factors that affect depression.
Methods
Subjects were 81 HSCT recipients undergoing leukemia at S Hospital in Seoul. Data was collected using self answering questionnaire from July 1th to June 30, 2002. The instruments included the Center for Epidemiologic Studies Depression Scale(CES-D) developed by Radloff(1977) and the State-Trait Anxiety Inventory developed by Spielberger(1975), and Self Respect Inventory(SRI) developed by Rosenberg(1965) and Family Support Scale developed by Choi(1983). Cronbach's a of each tool were 0.87, 0.93(State), 0.86(Trait), 0.76 and 0.82. Data was analyzed using SAS 8.1 by applying ttest, repeated measured ANOVA, Pearson correlation analysis and stepwise multiple regression.
Results
1. Depression was 22.6+10.1 which was higher than 16.0, named clinically depressive. 2. The level of depression was different significantly by gender, disease state before HSCT, and discomfort(p=0.01, p=0.00, p=0.00). 3. Depression was positively correlated with anxiety, fatigue, and negatively correlated with self respect. 4. Major factors that affect to depression in HSCT with leukemia was anxiety, which had an explanation of 41.2%.
Conclusions
Therefore, depression in HSCT with leukemia was influenced by various factors, so it should be generally screened and other various factors should be looked into. Additionally, according to the recipients specific needs, specified nursing intervention should be developed and applied to reduce their depression and promote psychological status.

Key Words: Hemopoietic stem cell transplantation; Depression